Synthetic ligustrazine based cyclohexanone and oxime analogs as Anti-Trypanosoma and Anti-Leishmanial agentes

In the present study a series of 34 synthetic ligustrazine-containing α, β-Unsaturated carbonyl-based compounds and oximes, recognized as anticancer compounds were assessed against protozoa of the Trypanosoma and Leishmania species. Ligustrazine, chemically known as tetramethylpyrazine (TMP), was se...

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Bibliographic Details
Main Authors: Abdulsalam A. M. Alkhaldi, Harry P. de Koning, Syed Nasir Abbas Bukhari
Format: Article
Language:English
Published: Universidade de São Paulo 2021-10-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502021000100524&tlng=en