Discovery of Small Molecule COX-1 and Akt Inhibitors as Anti-NSCLC Agents Endowed with Anti-Inflammatory Action

Targeted therapies have come into prominence in the ongoing battle against non-small cell lung cancer (NSCLC) because of the shortcomings of traditional chemotherapy. In this context, indole-based small molecules, which were synthesized efficiently, were subjected to an in vitro colorimetric assay t...

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Bibliographic Details
Main Authors: Mehlika Dilek Altıntop, Gülşen Akalın Çiftçi, Nalan Yılmaz Savaş, İpek Ertorun, Betül Can, Belgin Sever, Halide Edip Temel, Özkan Alataş, Ahmet Özdemir
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/3/2648