HIF-2α regulates proliferation, invasion, and metastasis of hepatocellular carcinoma cells via VEGF/Notch1 signaling axis after insufficient radiofrequency ablation

HIF-2α regulates proliferation, invasion, and metastasis of hepatocellular carcinoma cells via VEGF/Notch1 signaling axis after insufficient radiofrequency ablation

Background and AimsAlthough insufficient radiofrequency ablation (RFA) promotes the recurrence and metastasis of liver cancer, the underlying mechanism remains unclear. This study aimed to investigate the role and mechanism of HIF-2α in hepatocellular carcinoma cells (HCCs) after Insufficient RFA.Me...

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Bibliographic Details
Main Authors: Yongguang Yang, Weifeng Chen, Weiheng Mai, Yi Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma
residual carcinoma
radiofrequency ablation
hypoxia-inducible factor-2α
metastasis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.998295/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.998295/full

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