Synthesis and anticancer activity of novel quinazolinone-based rhodanines

Synthesis and anticancer activity of novel quinazolinone-based rhodanines

Abstract Background Rhodanines and quinazolinones have been reported to possess various pharmacological activities. Results A novel series of twenty quinazolinone-based rhodanines were synthesized via Knoevenagel condensation between 4-[3-(substitutedphenyl)-3,4-dihydro-4-oxoquinazolin-2-yl)methoxy]...

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Bibliographic Details
Main Authors: Sherihan El-Sayed, Kamel Metwally, Abdalla A. El-Shanawani, Lobna M. Abdel-Aziz, Harris Pratsinis, Dimitris Kletsas
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Chemistry Central Journal
Subjects:
Rhodanines
Anticancer
Apoptosis
Reactive oxygen species
Online Access:http://link.springer.com/article/10.1186/s13065-017-0333-x

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http://link.springer.com/article/10.1186/s13065-017-0333-x

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