miR-30-5p-mediated ferroptosis of trophoblasts is implicated in the pathogenesis of preeclampsia

Oxidative stress is a major cause of adverse outcomes in preeclampsia (PE). Ferroptosis, i.e. programmed cell death from iron-dependent lipid peroxidation, likely mediates PE pathogenesis. We evaluated specific markers for ferroptosis in normal and PE placental tissues, using in vitro (trophoblasts)...

Full description

Bibliographic Details
Main Authors: Heng Zhang, Yue He, Jian-xia Wang, Ming-hua Chen, Jian-juan Xu, Min-hui Jiang, Ya-ling Feng, Yan-fang Gu
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S221323171930919X