Human Patient-Derived Brain Tumor Models to Recapitulate Ependymoma Tumor Vasculature

Despite in vivo malignancy, ependymoma lacks cell culture models, thus limiting therapy development. Here, we used a tunable three-dimensional (3D) culture system to approximate the ependymoma microenvironment for recapitulating a patient’s tumor in vitro. Our data showed that the inclusion of VEGF...

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Bibliographic Details
Main Authors: Min D. Tang-Schomer, Markus J. Bookland, Jack E. Sargent, Taylor N. Jackvony
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/10/7/840