microRNA-194 is increased in polycystic ovary syndrome granulosa cell and induce KGN cells apoptosis by direct targeting heparin-binding EGF-like growth factor

microRNA-194 is increased in polycystic ovary syndrome granulosa cell and induce KGN cells apoptosis by direct targeting heparin-binding EGF-like growth factor

Abstract Background Polycystic ovary syndrome (PCOS) is an endocrine-related follicular developmental disorder that affects 50 %-70 % of reproductive-aged women diagnosed with ovulation-related infertility. Abnormal proliferation and apoptosis of granulosa cells (GCs) are thought to be the critical...

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Bibliographic Details
Main Authors: Yi-xuan Wu, Yan-shan Lin, Si-chen Li, Xi Yao, Mingwei Cheng, Lin Zhu, Hai-ying Liu
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Reproductive Biology and Endocrinology
Subjects:
miRNA
Cell growth
Granulosa cells
PCOS
Online Access:https://doi.org/10.1186/s12958-021-00850-w

Internet

https://doi.org/10.1186/s12958-021-00850-w

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