Coupling Mass Spectral and Genomic Information to Improve Bacterial Natural Product Discovery Workflows

Bacterial natural products possess potent bioactivities and high structural diversity and are typically encoded in biosynthetic gene clusters. Traditional natural product discovery approaches rely on UV- and bioassay-guided fractionation and are limited in terms of dereplication. Recent advances in...

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Bibliographic Details
Main Author: Max Crüsemann
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/19/3/142