A GalNAc/Gal-specific lectin from the sea mussel Crenomytilus grayanus modulates immune response in macrophages and in mice

Abstract A GalNAc/Gal-specific lectin (CGL) from the edible mussel Crenomytilus grayanus has been demonstrated to exhibit antibacterial properties. However, the mechanism of immune modulation by CGL in mammalian cells remains unclear. Here, we demonstrated that CGL can activate immune responses in m...

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Bibliographic Details
Main Authors: Oleg V. Chernikov, Wei-Ting Wong, Lan-Hui Li, Irina V. Chikalovets, Valentina I. Molchanova, Shih-Hsiung Wu, Jiahn-Haur Liao, Kuo-Feng Hua
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06647-5