Rational Design of Aptamer-Tagged tRNAs

Reprogramming of the genetic code system is limited by the difficulty in creating new tRNA structures. Here, I developed translationally active tRNA variants tagged with a small hairpin RNA aptamer, using <i>Escherichia coli</i> reporter assay systems. As the tRNA chassis for engineering...

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Bibliographic Details
Main Author: Takahito Mukai
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/20/7793