Insights into the Pharmacokinetics and In Vitro Cell-Based Studies of the Imidazoline I<sub>2</sub> Receptor Ligand B06

Insights into the Pharmacokinetics and In Vitro Cell-Based Studies of the Imidazoline I<sub>2</sub> Receptor Ligand B06

The impact of neurodegenerative diseases (ND) is becoming unbearable for humankind due to their vast prevalence and the lack of efficacious treatments. In this scenario, we focused on imidazoline I<sub>2</sub> receptors (I<sub>2</sub>-IR) that are widely distributed in the br...

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Bibliographic Details
Main Authors: Andrea Bagán, José A. Morales-García, Christian Griñán-Ferré, Caridad Díaz, José Pérez del Palacio, Maria C. Ramos, Francisca Vicente, Belén Pérez, José Brea, María Isabel Loza, Mercè Pallàs, Carmen Escolano
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
imidazoline I<sub>2</sub> receptor ligand
pharmacokinetics
bicyclic α-iminophosphonate
metabolic profile
neuroprotection
Alzheimer’s disease
Online Access:https://www.mdpi.com/1422-0067/23/10/5408

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https://www.mdpi.com/1422-0067/23/10/5408

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