Dabigatran and Wet AMD, Results From Retinal Pigment Epithelial Cell Monolayers, the Mouse Model of Choroidal Neovascularization, and Patients From the Medicare Data Base

Dabigatran and Wet AMD, Results From Retinal Pigment Epithelial Cell Monolayers, the Mouse Model of Choroidal Neovascularization, and Patients From the Medicare Data Base

BackgroundAge-related macular degeneration (AMD), the leading cause of irreversible blindness in elderly Caucasian populations, includes destruction of the blood-retina barrier (BRB) generated by the retinal pigment epithelium-Bruch’s membrane complex (RPE/BrM), and complement activation. Thrombin i...

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Bibliographic Details
Main Authors: Tanjina Akter, Balasubramaniam Annamalai, Elisabeth Obert, Kit N. Simpson, Bärbel Rohrer
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
VEGF
CTGF
complement
retinal pigment epithelium
mouse CNV
MarketScan
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.896274/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.896274/full

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