A Systematic Review of the Heterogenous Gene Expression Patterns Associated with Multidrug Chemoresistance in Conventional Osteosarcoma

Multidrug chemoresistance (MDR) remains the most significant obstacle to improving survival in osteosarcoma patients. Heterogeneous genetic alterations characterise the tumour microenvironment, and host molecular markers have been associated with MDR. This systematic review examines the genetic alte...

Full description

Bibliographic Details
Main Authors: Phakamani Goodman Mthethwa, Leonard Charles Marais, Veron Ramsuran, Collen Michelle Aldous
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/14/4/832