Embedding and Backscattered Scanning Electron Microscopy (EM-BSEM) Is Preferential over Immunophenotyping in Relation to Bioprosthetic Heart Valves

Embedding and Backscattered Scanning Electron Microscopy (EM-BSEM) Is Preferential over Immunophenotyping in Relation to Bioprosthetic Heart Valves

Hitherto, calcified aortic valves (AVs) and failing bioprosthetic heart valves (BHVs) have been investigated by similar approaches, mostly limited to various immunostaining techniques. Having employed multiple immunostaining combinations, we demonstrated that AVs retain a well-defined cellular hiera...

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Bibliographic Details
Main Authors: Alexander Kostyunin, Tatiana Glushkova, Elena Velikanova, Rinat Mukhamadiyarov, Leo Bogdanov, Tatiana Akentyeva, Evgeny Ovcharenko, Alexey Evtushenko, Daria Shishkova, Yulia Markova, Anton Kutikhin
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
bioprosthetic heart valves
structural valve degeneration
calcific aortic stenosis
calcific aortic valve disease
cell plasticity
immunophenotyping
Online Access:https://www.mdpi.com/1422-0067/24/17/13602

Internet

https://www.mdpi.com/1422-0067/24/17/13602

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