Interleukin‐6 signaling requires only few IL‐6 molecules: Relation to physiological concentrations of extracellular IL‐6
Abstract Introduction The aim of this study was to give quantitative insight into the number of cytokine molecules needed to activate a target cell and relate this to the physiological consequences of the amounts of cytokines typically detectable in humans. As a model system blood interleukin‐6 (IL‐...
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Format: | Article |
Language: | English |
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Wiley
2020-06-01
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Series: | Immunity, Inflammation and Disease |
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Online Access: | https://doi.org/10.1002/iid3.292 |