Pyrazine based novel molecules as potential therapeutic agents: Synthesis, in vitro biological screening, in silico ADMET profiling and molecular docking study

Pyrazine based novel molecules as potential therapeutic agents: Synthesis, in vitro biological screening, in silico ADMET profiling and molecular docking study

The current study described the synthesis of pyrazine-based novel molecules (1–15) using stepwise processes and their structures have been identified using various characterization techniques such as 1HNMR, 13CNMR, and HREI-MS. Furthermore, biological assessment of these scaffolds as anti-Alzheimer,...

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Bibliographic Details
Main Authors: Rafaqat Hussain, Wagma Hassan, Fazal Rahim, Shazia Subhan, Zakia Subhan, Shoaib Khan, Amjad Hussain, Hayat Ullah, Muhammad Nabi, Riaz Ullah, Essam A. Ali, Saltanat Aghayeva
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:Results in Chemistry
Subjects:
Pyrazine
AChE
Anti-bacterial
Anti-fungal
Molecular docking
ADMET properties
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715624003941

Internet

http://www.sciencedirect.com/science/article/pii/S2211715624003941

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