Implication of Lactucopicrin in Autophagy, Cell Cycle Arrest and Oxidative Stress to Inhibit U87Mg Glioblastoma Cell Growth
In this study, we propose lactucopicrin (LCTP), a natural sesquiterpene lactone from Lactucavirosa, as a molecule able to control the growth of glioblastoma continuous cell line U87Mg. The IC50 of U87Mg against LCTP revealed a strong cytotoxic effect. Daily administration of LCTP showed a dose and t...
Main Authors: | Rossella Rotondo, Maria Antonietta Oliva, Sabrina Staffieri, Salvatore Castaldo, Felice Giangaspero, Antonietta Arcella |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-12-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/24/5843 |
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