Urban Particulate Matter Enhances ROS/IL-6/COX-II Production by Inhibiting MicroRNA-137 in Synovial Fibroblast of Rheumatoid Arthritis

Urban Particulate Matter Enhances ROS/IL-6/COX-II Production by Inhibiting MicroRNA-137 in Synovial Fibroblast of Rheumatoid Arthritis

Background: Rheumatoid arthritis (RA) has been associated with air pollution, possibly due to the augmentation of inflammatory effects. In this study, we aimed to determine the roles of inflammatory pathways and microRNA involved in the pathogenesis of RA fibroblast-like synoviocytes (FLS) inflammat...

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Bibliografski detalji
Glavni autori: Ming-Horng Tsai, Miao-Ching Chi, Jen-Fu Hsu, I-Ta Lee, Ko-Ming Lin, Mei-Ling Fang, Ming-Hsueh Lee, Chiang-Wen Lee, Ju-Fang Liu
Format: Članak
Jezik:English
Izdano: MDPI AG 2020-06-01
Serija:Cells
Teme:
particulate matter
air pollution
rheumatoid arthritis
reactive oxidative stress
interleukin-6
inflammation
Online pristup:https://www.mdpi.com/2073-4409/9/6/1378

Internet

https://www.mdpi.com/2073-4409/9/6/1378

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