Zn/Ga−DFO iron–chelating complex attenuates the inflammatory process in a mouse model of asthma

Zn/Ga−DFO iron–chelating complex attenuates the inflammatory process in a mouse model of asthma

Background: Redox-active iron, a catalyst in the production of hydroxyl radicals via the Fenton reaction, is one of the key participants in ROS-induced tissue injury and general inflammation. According to our recent findings, an excess of tissue iron is involved in several airway-related pathologies...

Full description

Bibliographic Details
Main Authors: Haim Bibi, Vladimir Vinokur, Dan Waisman, Yigal Elenberg, Amir Landesberg, Anna Faingersh, Moran Yadid, Vera Brod, Jimy Pesin, Eduard Berenshtein, Ron Eliashar, Mordechai Chevion
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Redox Biology
Subjects:
Asthma
OVA-induced asthma model
Inflammation
Iron
Iron chelation
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231714000810

Internet

http://www.sciencedirect.com/science/article/pii/S2213231714000810

Similar Items