Small molecule cognitive enhancer reverses age-related memory decline in mice

Small molecule cognitive enhancer reverses age-related memory decline in mice

With increased life expectancy, age-associated cognitive decline becomes a growing concern, even in the absence of recognizable neurodegenerative disease. The integrated stress response (ISR) is activated during aging and contributes to age-related brain phenotypes. We demonstrate that treatment wit...

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Bibliographic Details
Main Authors: Karen Krukowski, Amber Nolan, Elma S Frias, Morgane Boone, Gonzalo Ureta, Katherine Grue, Maria-Serena Paladini, Edward Elizarraras, Luz Delgado, Sebastian Bernales, Peter Walter, Susanna Rosi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-12-01
Series:eLife
Subjects:
aging
ISR
memory
immune dysfunction
Online Access:https://elifesciences.org/articles/62048

Internet

https://elifesciences.org/articles/62048

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