Resilience of BST-2/Tetherin structure to single amino acid substitutions
Human tetherin, also known as BST-2 or CD317, is a dimeric, extracellular membrane-bound protein that consists of N and C terminal membrane anchors connected by an extracellular domain. BST-2 is involved in binding enveloped viruses, such as HIV, and inhibiting viral release in addition to a role in...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2019-05-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/7043.pdf |