Mathematical model explains differences in Omicron and Delta SARS-CoV-2 dynamics in Caco-2 and Calu-3 cells

Within-host infection dynamics of Omicron dramatically differs from previous variants of SARS-CoV-2. However, little is still known about which parameters of virus-cell interplay contribute to the observed attenuated replication and pathogenicity of Omicron. Mathematical models, often expressed as s...

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Bibliographic Details
Main Authors: Vladimir Staroverov, Alexei Galatenko, Evgeny Knyazev, Alexander Tonevitsky
Format: Article
Language:English
Published: PeerJ Inc. 2024-03-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/16964.pdf