The force of the myosin motor sets cooperativity in thin filament activation of skeletal muscles

Sarcomeres of Ca2 + -activated demembranated fibres of rabbit soleus muscles show that the stress exerted by each motor protein on the thin filament determines the cooperativity in thin filament activation. 

Bibliographic Details
Main Authors: Marco Caremani, Matteo Marcello, Ilaria Morotti, Irene Pertici, Caterina Squarci, Massimo Reconditi, Pasquale Bianco, Gabriella Piazzesi, Vincenzo Lombardi, Marco Linari
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-04184-0