Adaptation of Arginine Synthesis among Uropathogenic Branches of the <named-content content-type="genus-species">Escherichia coli</named-content> Phylogeny Reveals Adjustment to the Urinary Tract Habitat

Adaptation of Arginine Synthesis among Uropathogenic Branches of the <named-content content-type="genus-species">Escherichia coli</named-content> Phylogeny Reveals Adjustment to the Urinary Tract Habitat

ABSTRACT Urinary tract infections (UTIs) are predominantly caused by uropathogenic Escherichia coli (UPEC). UPEC pathogenesis requires passage through a severe population bottleneck involving intracellular bacterial communities (IBCs) that are clonal expansions of a single invading UPEC bacterium in...

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Bibliographic Details
Main Authors: Michael E. Hibbing, Karen W. Dodson, Vasilios Kalas, Swaine L. Chen, Scott J. Hultgren
Format: Article
Language:English
Published: American Society for Microbiology 2020-10-01
Series:mBio
Subjects:
Escherichia coli
arginine metabolism
positive selection
urinary tract infection
Online Access:https://journals.asm.org/doi/10.1128/mBio.02318-20

Internet

https://journals.asm.org/doi/10.1128/mBio.02318-20

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