Development of the method for determinating ADCC biological activity of IVIG

Development of the method for determinating ADCC biological activity of IVIG

Objective To establish a method for determinating the antigen-dependent cell-mediated cytotoxicity (ADCC) of human immunoglobulin (pH4)for intravenous injection (IVIG) on luciferase reporter gene-modified cell assay. Methods As effector cells, Jurkat-NFAT-Luc-CD16 cells were used in the assay, and P...

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Bibliographic Details
Main Authors: Liyuan ZHU, Qing LIU, Li MA, Changqing LI
Format: Article
Language:zho
Published: Institute of Blood Transfusion of Chinese Academy of Medical Sciences 2023-02-01
Series:Zhongguo shuxue zazhi
Subjects:
human immunoglobulin (ph4)for intravenous injection
fc fragment
antibody-dependent cell-mediated cytotoxicity
biological activity
Online Access:https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2023.02.007&lang=en

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https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2023.02.007&lang=en

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