Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism.

Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism.

Interleukin (IL)-32 is a newly described proinflammatory cytokine that seems likely to play a role in inflammation and host defense. Little is known about the regulation of IL-32 production by primary cells of the immune system.In the present study, freshly obtained human peripheral blood mononuclea...

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Bibliographic Details
Main Authors: Mihai G Netea, Tania Azam, Eli C Lewis, Leo A B Joosten, Maorong Wang, Dennis Langenberg, Xianzhong Meng, Edward D Chan, Do-Young Yoon, Tom Ottenhoff, Soo-Hyun Kim, Charles A Dinarello
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-08-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1539091?pdf=render

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http://europepmc.org/articles/PMC1539091?pdf=render

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