The response of the prostate to circulating cholesterol: activating transcription factor 3 (ATF3) as a prominent node in a cholesterol-sensing network.

Elevated circulating cholesterol is a systemic risk factor for cardiovascular disease and metabolic syndrome, however the manner in which the normal prostate responds to variations in cholesterol levels is poorly understood. In this study we addressed the molecular and cellular effects of elevated a...

Full description

Bibliographic Details
Main Authors: Jayoung Kim, Dolores Di Vizio, Taek-Kyun Kim, Jonghwan Kim, Minjung Kim, Kristine Pelton, Steven K Clinton, Tsonwin Hai, Daehee Hwang, Keith R Solomon, Michael R Freeman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3388073?pdf=render