Impact of exposure to malaria and nutritional status on responses to the experimental malaria vaccine ChAd63 MVA ME-TRAP in 5-17 month-old children in Burkina Faso

Impact of exposure to malaria and nutritional status on responses to the experimental malaria vaccine ChAd63 MVA ME-TRAP in 5-17 month-old children in Burkina Faso

The experimental malaria vaccine ChAd63 MVA ME-TRAP previously showed protective efficacy against Plasmodium falciparum infection in Phase IIa sporozoite challenge studies in adults in the United Kingdom and in a Phase IIb field efficacy trial in Kenyan adults. However, it failed to demonstrate effi...

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Bibliographic Details
Main Authors: Richard Morter, Alfred B. Tiono, Issa Nébié, Oliver Hague, Alphonse Ouedraogo, Amidou Diarra, Nicola K. Viebig, Adrian V. S. Hill, Katie J. Ewer, Sodiomon B. Sirima
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
malaria
vaccine
viral vector
ME-TRAP
Burkina Faso
immunosuppression
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1058227/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1058227/full

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