Promotion of Erythropoietic Differentiation in Hematopoietic Stem Cells by SOCS3 Knock-Down.

Promotion of Erythropoietic Differentiation in Hematopoietic Stem Cells by SOCS3 Knock-Down.

Suppressor of cytokine signaling 3 (SOCS3) plays an important role in mice fetal liver erythropoiesis, but the roles of SOCS3 in human hematopoietic stem cells (HSCs) have not been well investigated. In the present study, lentiviral small interference RNA expression vectors (shRNA) of SOCS3 were con...

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Bibliographic Details
Main Authors: Yu-xiao Liu, Xing Dong, Feng Gong, Ning Su, Su-bo Li, Hai-tao Zhang, Jia-ling Liu, Jing-hui Xue, Shou-ping Ji, Zhi-wen Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4529111?pdf=render

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http://europepmc.org/articles/PMC4529111?pdf=render

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