Integrating knowledge and omics to decipher mechanisms via large‐scale models of signaling networks

Abstract Signal transduction governs cellular behavior, and its dysregulation often leads to human disease. To understand this process, we can use network models based on prior knowledge, where nodes represent biomolecules, usually proteins, and edges indicate interactions between them. Several comp...

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Bibliographic Details
Main Authors: Martin Garrido‐Rodriguez, Katharina Zirngibl, Olga Ivanova, Sebastian Lobentanzer, Julio Saez‐Rodriguez
Format: Article
Language:English
Published: Springer Nature 2022-07-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.202211036