The Impact of Apolipoprotein E (<i>APOE</i>) Epigenetics on Aging and Sporadic Alzheimer’s Disease

The Impact of Apolipoprotein E (<i>APOE</i>) Epigenetics on Aging and Sporadic Alzheimer’s Disease

Sporadic Alzheimer’s disease (AD) derives from an interplay among environmental factors and genetic variants, while epigenetic modifications have been expected to affect the onset and progression of its complex etiopathology. Carriers of one copy of the apolipoprotein E gene (<i>APOE</i>...

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Bibliographic Details
Main Authors: Madia Lozupone, Vittorio Dibello, Rodolfo Sardone, Fabio Castellana, Roberta Zupo, Luisa Lampignano, Ilaria Bortone, Antonio Daniele, Antonello Bellomo, Vincenzo Solfrizzi, Francesco Panza
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Biology
Subjects:
apolipoprotein E
Alzheimer’s disease
methylation
dementia
epigenetics
tau protein
Online Access:https://www.mdpi.com/2079-7737/12/12/1529

Internet

https://www.mdpi.com/2079-7737/12/12/1529

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