Infant Gut Microbial Metagenome Mining of α-l-Fucosidases with Activity on Fucosylated Human Milk Oligosaccharides and Glycoconjugates

Infant Gut Microbial Metagenome Mining of α-l-Fucosidases with Activity on Fucosylated Human Milk Oligosaccharides and Glycoconjugates

ABSTRACT The gastrointestinal microbiota members produce α-l-fucosidases that play key roles in mucosal, human milk, and dietary oligosaccharide assimilation. Here, 36 open reading frames (ORFs) coding for putative α-l-fucosidases belonging to glycosyl hydrolase family 29 (GH29) were identified thro...

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Bibliographic Details
Main Authors: Eva M. Moya-Gonzálvez, Nazaret Peña-Gil, Antonio Rubio-del-Campo, José M. Coll-Marqués, Roberto Gozalbo-Rovira, Vicente Monedero, Jesús Rodríguez-Díaz, María J. Yebra
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:Microbiology Spectrum
Subjects:
α-l-fucosidase
metagenome
microbiota
infant gut
human milk oligosaccharides
histo-blood group antigens
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01775-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.01775-22

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