Molecular evolution and functional divergence of the Ca(2+) sensor protein in store-operated Ca(2+) entry: stromal interaction molecule.
Receptor-mediated Ca(2+) signaling in many non-excitable cells initially induces Ca(2+) release from intracellular Ca(2+) stores, followed by Ca(2+) influx across the plasma membrane. Recent findings have suggested that stromal interaction molecules (STIMs) function as the Ca(2+) sensor to detect ch...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2007-07-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC1904252?pdf=render |