Spatiotemporal control of mitotic exit during anaphase by an aurora B-Cdk1 crosstalk

Spatiotemporal control of mitotic exit during anaphase by an aurora B-Cdk1 crosstalk

According to the prevailing ‘clock’ model, chromosome decondensation and nuclear envelope reformation when cells exit mitosis are byproducts of Cdk1 inactivation at the metaphase-anaphase transition, controlled by the spindle assembly checkpoint. However, mitotic exit was recently shown to be a func...

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Bibliographic Details
Main Authors: Olga Afonso, Colleen M Castellani, Liam P Cheeseman, Jorge G Ferreira, Bernardo Orr, Luisa T Ferreira, James J Chambers, Eurico Morais-de-Sá, Thomas J Maresca, Helder Maiato
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-08-01
Series:eLife
Subjects:
mitosis
anaphase
Aurora B
Cyclin B1
Cdk1
mitotic exit
Online Access:https://elifesciences.org/articles/47646

Internet

https://elifesciences.org/articles/47646

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