Insight into the nucleoside transport and inhibition of human ENT1

Insight into the nucleoside transport and inhibition of human ENT1

The human equilibrative nucleoside transporter 1 (hENT1) is an effective controller of adenosine signaling by regulating its extracellular and intracellular concentration, and has become a solid drug target of clinical used adenosine reuptake inhibitors (AdoRIs). Currently, the mechanisms of adenosi...

Full description

Bibliographic Details
Main Authors: Zhixiang Wu, Zhongjie Han, Wenxue Zhou, Xiaohan Sun, Lei Chen, Shuang Yang, Jianping Hu, Chunhua Li
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Current Research in Structural Biology
Subjects:
hENT1
Nucleoside transport
Adenosine
Dilazep
Inhibition mechanism
Online Access:http://www.sciencedirect.com/science/article/pii/S2665928X22000174

Internet

http://www.sciencedirect.com/science/article/pii/S2665928X22000174

Similar Items