Distinct transcriptional signatures in purified circulating immune cells drive heterogeneity in disease location in IBD

Objective To infer potential mechanisms driving disease subtypes among patients with inflammatory bowel disease (IBD), we profiled the transcriptome of purified circulating monocytes and CD4 T-cells.Design RNA extracted from purified monocytes and CD4 T-cells derived from the peripheral blood of 125...

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Bibliographic Details
Main Authors: Séverine Vermeire, Marc Ferrante, Padhmanand Sudhakar, Bram Verstockt, Jonathan Cremer, João Sabino, Sare Verstockt
Format: Article
Language:English
Published: BMJ Publishing Group 2023-11-01
Series:BMJ Open Gastroenterology
Online Access:https://bmjopengastro.bmj.com/content/10/1/e001003.full