Visualization of probiotic-mediated Ca2+ signaling in intestinal epithelial cells in vivo

Probiotics, such as lactic acid bacteria (LAB) and Bacillus subtilis var. natto, have been shown to modulate immune responses. It is important to understand how probiotic bacteria impact intestinal epithelial cells (IECs), because IECs are the first line of defense at the mucosal surface barrier and...

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Main Authors: Takahiro Adachi, Shigeru Kakuta, Yoshiko Aihara, Tomonori Kamiya, Yohei Watanabe, Naomi Osakabe, Naoki Hasato, Atsushi Miyawaki, Soichiro Yoshikawa, Takako Usami, Hajime Karasuyama, Hiromi Kimoto-Nira, Kazuhiro Hirayama, Noriko Tsuji
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00601/full