Inhibition of lysyl oxidase‐like 2 overcomes adhesion‐dependent drug resistance in the collagen‐enriched liver cancer microenvironment

Inhibition of lysyl oxidase‐like 2 overcomes adhesion‐dependent drug resistance in the collagen‐enriched liver cancer microenvironment

Abstract The tumor microenvironment (TME) is considered to be one of the vital mediators of tumor progression. Extracellular matrix (ECM), infiltrating immune cells, and stromal cells collectively constitute the complex ecosystem with varied biochemical and biophysical properties. The development of...

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Main Authors: Lanqi Gong, Yu Zhang, Yuma Yang, Qian Yan, Jifeng Ren, Jie Luo, Yuen Chak Tiu, Xiaona Fang, Beilei Liu, Raymond Hiu Wai Lam, Ka‐On Lam, Anne Wing‐Mui Lee, Xin‐Yuan Guan
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2022-11-01
Series:Hepatology Communications
Online Access:https://doi.org/10.1002/hep4.1966

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https://doi.org/10.1002/hep4.1966

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