Semi-Quantitatively Designing Two-Photon High-Performance Fluorescent Probes for Glutathione S-Transferases

Glutathione S-transferases (GSTs), detoxification enzymes that catalyze the addition of glutathione (GSH) to diverse electrophilic molecules, are often overexpressed in various tumor cells. While fluorescent probes for GSTs have often adopted the 2,4-dinitrobenzenesulfonyl (DNs) group as the recepto...

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Bibliographic Details
Main Authors: Xue-Xiang Zhang, Huan Qi, Mei-Heng Lu, Song-Qiu Yang, Peng Li, Hai-long Piao, Ke-Li Han
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2020-01-01
Series:Research
Online Access:http://dx.doi.org/10.34133/2020/7043124