Targeting neuroblastoma stem cells with retinoic acid and proteasome inhibitor.

BACKGROUND:Neuroblastma cell lines contain a side-population of cells which express stemness markers. These stem-like cells may represent the potential underlying mechanism for resistance to conventional therapy and recurrence of neuroblastoma in patients. METHODOLOGY/PRINCIPAL FINDINGS:To develop n...

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Bibliographic Details
Main Authors: Barbara Hämmerle, Yania Yañez, Sarai Palanca, Adela Cañete, Deborah J Burks, Victoria Castel, Jaime Font de Mora
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3792090?pdf=render