Targeting cytosolic proliferating cell nuclear antigen (PCNA) in neutrophil-dominated inflammation

Targeting cytosolic proliferating cell nuclear antigen (PCNA) in neutrophil-dominated inflammation

New therapeutic approaches that can accelerate neutrophil apoptosis under inflammatory conditions to enhance the resolution of inflammation are now under study. Neutrophils are deprived of proliferative capacity and have a tightly controlled lifespan to avoid their persistence at the site of injury....

Full description

Bibliographic Details
Main Authors: Alessia eDe Chiara, Magali ePederzoli-Ribeil, Pierre-Régis eBurgel, Claire eDanel, Véronique eWitko-Sarsat
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-10-01
Series:Frontiers in Immunology
Subjects:
Apoptosis
Cystic Fibrosis
Inflammation
Neutrophil
PCNA
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00311/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00311/full

Similar Items