Piplartine Synthetic Analogs: In Silico Analysis and Antiparasitic Study against <i>Trypanosoma cruzi</i>

Piplartine Synthetic Analogs: In Silico Analysis and Antiparasitic Study against <i>Trypanosoma cruzi</i>

Neglected tropical diseases (NTDs) cause thousands of deaths each year. Among these diseases, we find Chagas disease, whose etiologic agent is <i>Trypanosoma cruzi.</i> Piplartine is an alkamide present in various species of the genus <i>Piper</i> that possess trypanocidal ac...

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Bibliographic Details
Main Authors: Rayanne H. N. Silva, Emanuel P. Magalhães, Rebeca C. Gomes, Yunierkis Perez-Castillo, Alice M. C. Martins, Damião P. de Sousa
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Applied Sciences
Subjects:
piperlongumine
cytotoxicity
natural products
trypanocide
alkaloid
<i>Trypanosoma</i>
Online Access:https://www.mdpi.com/2076-3417/13/20/11585

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https://www.mdpi.com/2076-3417/13/20/11585

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