Novel Dichloroacetophenone-Based PDHK1 Inhibitors as Potent Anticancer Agents

Novel Dichloroacetophenone-Based PDHK1 Inhibitors as Potent Anticancer Agents

Puhua Wu,1,2 Zhicheng Zhang,1 Yan Zhou,2 Quan Liu,2 Kin-Yip Tam,2 Zhenhong Su1 1Hubei Key Laboratory for Kidney Disease Pathogenesis and Intervention, School of Medicine, Hubei Polytechnic University, Huangshi, People’s Republic of China; 2Cancer Centre, Faculty of Health Sciences, University of Mac...

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Bibliographic Details
Main Authors: Wu P, Zhang Z, Zhou Y, Liu Q, Tam KY, Su Z
Format: Article
Language:English
Published: Dove Medical Press 2024-10-01
Series:Drug Design, Development and Therapy
Subjects:
pdhk1
dichloroacetophenone
allosteric pocket
anti-nsclc activity
tumor xenograft mouse model
Online Access:https://www.dovepress.com/novel-dichloroacetophenone-based-pdhk1-inhibitors-as-potent-anticancer-peer-reviewed-fulltext-article-DDDT

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https://www.dovepress.com/novel-dichloroacetophenone-based-pdhk1-inhibitors-as-potent-anticancer-peer-reviewed-fulltext-article-DDDT

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