Autophagy and Neurodegeneration: Insights from a Cultured Cell Model of ALS

Autophagy plays a major role in the elimination of cellular waste components, the renewal of intracellular proteins and the prevention of the build-up of redundant or defective material. It is fundamental for the maintenance of homeostasis and especially important in post-mitotic neuronal cells, whi...

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Bibliographic Details
Main Authors: Francesca Navone, Paola Genevini, Nica Borgese
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/4/3/354