Deciphering Genomic Heterogeneity and the Internal Composition of Tumour Activities through a Hierarchical Factorisation Model

Genomic heterogeneity constitutes one of the most distinctive features of cancer diseases, limiting the efficacy and availability of medical treatments. Tumorigenesis emerges as a strongly stochastic process, producing a variable landscape of genomic configurations. In this context, matrix factorisa...

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Bibliographic Details
Main Authors: José Carbonell-Caballero, Antonio López-Quílez, David Conesa, Joaquín Dopazo
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Mathematics
Subjects:
Online Access:https://www.mdpi.com/2227-7390/9/21/2833