APC and AXIN2 Are Promising Biomarker Candidates for the Early Detection of Adenomas and Hyperplastic Polyps

Aberrant activation of the WNT/CTNNB1 pathway is notorious in colorectal cancer (CRC). Here, we demonstrate that the expression of specific and crucial WNT signaling pathway genes is linked to disease progression in colonic adenomatous (AP) and hyperplastic (HP) polyps in an Iranian patient populati...

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Main Authors: Sama Rezasoltani, Mahrooyeh Hadizadeh, Mina Golmohammadi, Ehsan Nazemalhossini-Mojarad, Sina Salari, Hamid Rezvani, Hamid Asadzadeh-Aghdaei, Michael Ladomery, Chris Young, Fakhrosadat Anaraki, Sarah Almond, Maziar Ashrafian Bonab
Format: Article
Language:English
Published: SAGE Publishing 2020-11-01
Series:Cancer Informatics
Online Access:https://doi.org/10.1177/1176935120972383