Effect of pregabalin on apoptotic regulatory genes in hippocampus of rats with chronic temporal lobe epilepsy
Objective To observe the effect of pregabalin on the expression of Bcl⁃2 and Bax in hippocampus of chronic epileptic rats induced by pilocarpine, to explore the anti⁃epileptic pharmacology mechanism of pregabalin, and its anti ⁃ apoptotic effect on hippocampal neurons of rats. Methods The model of c...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Tianjin Huanhu Hospital
2012-04-01
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Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
Subjects: | |
Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/147 |