Hidden modes of DNA binding by human nuclear receptors

Hidden modes of DNA binding by human nuclear receptors

Abstract Human nuclear receptors (NRs) are a superfamily of ligand-responsive transcription factors that have central roles in cellular function. Their malfunction is linked to numerous diseases, and the ability to modulate their activity with synthetic ligands has yielded 16% of all FDA-approved dr...

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Bibliographic Details
Main Authors: Devesh Bhimsaria, José A. Rodríguez-Martínez, Jacqui L. Mendez-Johnson, Debostuti Ghoshdastidar, Ashwin Varadarajan, Manju Bansal, Danette L. Daniels, Parameswaran Ramanathan, Aseem Z. Ansari
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39577-0

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https://doi.org/10.1038/s41467-023-39577-0

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