Genomic Surveillance of Vancomycin-Resistant Enterococcus faecium Reveals Spread of a Linear Plasmid Conferring a Nutrient Utilization Advantage

Genomic Surveillance of Vancomycin-Resistant Enterococcus faecium Reveals Spread of a Linear Plasmid Conferring a Nutrient Utilization Advantage

ABSTRACT Healthcare-associated outbreaks of vancomycin-resistant Enterococcus faecium (VREfm) are a worldwide problem with increasing prevalence. The genomic plasticity of this hospital-adapted pathogen contributes to its efficient spread despite infection control measures. Here, we aimed to identif...

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Bibliographic Details
Main Authors: Mathilde Boumasmoud, Vanina Dengler Haunreiter, Tiziano A. Schweizer, Lilly Meyer, Bhavya Chakrakodi, Peter W. Schreiber, Kati Seidl, Denise Kühnert, Roger D. Kouyos, Annelies S. Zinkernagel
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:mBio
Subjects:
Enterococcus faecium
transmission networks
linear plasmid
N-acetyl-galactosamine
horizontal gene transfer
Online Access:https://journals.asm.org/doi/10.1128/mbio.03771-21

Internet

https://journals.asm.org/doi/10.1128/mbio.03771-21

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