Chemical tuning of photoswitchable azobenzenes: a photopharmacological case study using nicotinic transmission

We have developed photochromic probes for the nicotinic acetylcholine receptor that exploit the unique chemical properties of the tetrafluoroazobenzene (4FAB) scaffold. Ultraviolet light switching and rapid thermal relaxation of the metastable cis configuration are the main drawbacks associated with...

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Bibliographic Details
Main Authors: Lorenzo Sansalone, Jun Zhao, Matthew T. Richers, Graham C. R. Ellis-Davies
Format: Article
Language:English
Published: Beilstein-Institut 2019-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.15.274